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• 產(chǎn)品描述： Suprofen is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.

• 靶點： COX;PGE Synthase;COX;PGESynthase

• 體內(nèi)研究：
  Suprofen combined with PGF2 alpha blocks induction of uterine contractions, suggesting the possibility that Suprofen also antagonizes PGF2 alpha receptor binding. Suprofen are effective at preventing BAB disruption after paracentesis in dogs, indicating their potential usefulness for treatment of prostaglandin-mediated ocular disease. Suprofen (3.7 mg/kg, i.v.) induces a marked decrease in the firing evoked in arthritic rats by ankle mobilization.

• 參考文獻：
  1. Cirli OO, et al. J Control Release, 2004, 96(1), 85-96. 2. Fujita H, et al. Photodermatol Photoimmunol Photomed, 11992-11993, 9(5), 203-208. 3. O'Donnell JP, et al. Drug Metab Dispos, 2003, 31(11), 1369-1377. 4. Hahn DW, et al. Prostaglandins, 1982, 23(1), 1-16. 5. Starrs SM, et al. Photochem Photobiol, 2000, 72(3), 291-297.

• 溶解性： Soluble  in  DMSO

• 保存條件： -20℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	3.842 ml	19.208 ml	38.416 ml
  5 mM	0.768 ml	3.842 ml	7.683 ml
  10 mM	0.384 ml	1.921 ml	3.842 ml
  50 mM	0.077 ml	0.384 ml	0.768 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *